Infectious Mononucleosis
Summary
EBV
Sore Throat + Fever + Lymphadenopathy
Supportive management
Pathophysiology
AKA Glandular Fever
Epstein-Barr Virus
Risk factors
- Kissing
- Sexual behaviour
Presentation
Classic Triad
- Sore Throat
- Pyrexia
- Lymphadenopathy
- Posterior triangle
Lymphadenopathy
Tonsillitis → Confined to Anterior cervical chain
Glandular fever → Posterior may be involved
Additional Features
-
Palatal petechiae
-
Splenomegaly
-
Transient ALT
-
Amoxicillin and ampicillin can cause maculopapular pruritic rash
Workup
- Clinical Diagnosis
- Confirmatory test in 2 weeks
- Heterophile antibody test (Monospot tests)
- FBC
- In the early stage, a high rate of false negatives
Management
- Supportive
- Avoid contact sport for 4 weeks to ↓ risk splenic rupture